Back to back fetal Heart Cell Atlas manuscripts now available on BioRxiv
Back to back fetal Heart Cell Atlas manuscripts now available on BioRxiv
The foundational manuscripts by CellTalk HHD members are now available on BioRxiv. The research covered in both manuscripts was carried out at the same time. On the one hand, the manuscript entitled “High-resolution atlas of the developing human heart and the great vessels” covers the cell type annotations, part of the coronary vasculature, and transcriptional states of structures seen in healthy development. On the other hand, the manuscript entitled “Multiomic analysis reveals developmental dynamics of the human heart in health and disease” discusses results pertaining to spatial transcriptomics, gene regulation, conductive system, and putative disease in the context of human heart development. Together, these articles offer a large and accessible resource and set the scene for the consortium’s focus over the next 5 years.
Read more at BioRxiv:
High-resolution atlas of the developing human heart and the great vessels
Semih Bayraktar, James Cranley, Kazumasa Kanemaru, Vincent Knight-Schrijver, Maria Colzani, Hongorzul Davaapil, Jonathan Chuo Min Lee, Krzysztof Polanski, Laura Richardson, Claudia I. Semprich, Rakeshlal Kapuge, Monika Dabrowska, Ilaria Mulas, Shani Perera, Minal Patel, Siew Yen Ho, Xiaoling He, Richard Tyser, Laure Gambardella, Sarah A. Teichmann, Sanjay Sinha
bioRxiv 2024.04.27.591127; doi: https://doi.org/10.1101/2024.04.27.591127
Multiomic analysis reveals developmental dynamics of the human heart in health and disease
James Cranley, Kazumasa Kanemaru, Semih Bayraktar, Vincent Knight-Schrijver, Jan Patrick Pett, Krzysztof Polanski, Monika Dabrowska, Ilaria Mulas, Laura Richardson, Claudia I. Semprich, Rakeshlal Kapuge, Shani Perera, Xiaoling He, Siew Yen Ho, Nadav Yayon, Liz Tuck, Kenny Roberts, Jack A. Palmer, Hongorzul Davaapil, Laure Gambardella, Minal Patel, Richard Tyser, Sanjay Sinha, Sarah A. Teichmann
bioRxiv 2024.04.29.591736; doi: https://doi.org/10.1101/2024.04.29.591736